产品货号：
Z14442
中文名称：
EP300抗体
英文名称：
Anti-EP300 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EP300 Antibody |
| 指标别名 | E1A associated protein p300;E1A binding protein p300;EP300;Histone acetyltransferase p300;KAT3B;p300;p300 HAT |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | EP300 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human KAT3B/p300/EP300 (MAQPPIVPRQTPPLQHH). |
| 实际分子量 | 264～300KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E1A binding protein p300 also known as EP300 or p300 is a protein that in humans is encoded by the EP300 gene.The EP300 gene is located on the long (q) arm of the human chromosome 22 at position 13.2.This protein regulates the activity of many genes in tissues throughout the body.It plays an essential role in regulating cell growth and division,prompting cells to mature and assume specialized functions (differentiate),and preventing the growth of cancerous tumors.The EP300 protein appears to be critical for normal development before and after birth.It carries out its function by activating transcription.In addition,the protein functions as histone acetyltransferase that regulates transcription via chromatin remodeling,and is important in the processes of cell proliferation and differentiation.EP300 also mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. |
| Uniprot ID | Q09472 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | E1A binding protein p300 |
| 蛋白名全称 | Histone acetyltransferase p300 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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